Thrombosis is the formation of a blood clot (thrombus) inside a blood vessel which obstructs the flow of blood through the circulatory system. When a blood vessel is injured, the body uses platelets and fibrin to form a blood clot to prevent blood loss. However, under certain conditions blood clots can form within the body, even when blood vessels are uninjured. Blood clots that become significantly large can reduce blood flow to a tissue and deprive the tissue of adequate oxygen (hypoxia). A larger thrombus can greatly reduce blood flow and completely deprive a tissue of oxygen, leading to tissue death.
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